Orphan Diseases

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"African sleeping sickness, leishmaniasis and Chagas disease are all examples of what are often termed "orphan diseases," because of the overall lack of attention paid to them by major drugmakers (despite afflicting millions of people every year). They are among the subjects of the Tropical Disease Initiative, an effort to develop open source medicines to fight orphan diseases." (http://www.worldchanging.com/archives/003122.html)